Does the risk of infective endarteritis justify routine patent ductus arteriosus closure?

Patent ductus arteriosus endarteritis in a 40-year old woman, diagnosed with Transesophageal Echocardiography. A case report and a brief review of the literature

Infective endarteritis (IE) was a fatal complication and the most common cause of death (45%) in patients with patent ductus arteriosus (PDA), before the introduction of antibiotic therapy and surgical closure of the ductus. The annual risk of IE in patients with PDA was estimated to be 0–45% [5]. Wide use of antibiotics and surgical closure of PDA has reduced significantly the incidence of IE ...

Mycotic aneurysm at site of formerly ligated ductus arteriosus caused by infective endarteritis.

The risk of developing infective endocarditis in relation to a pre-existing cardiac lesion varies according to the lesion. In persistent ductus arteriosus it is approximately one in every 300 patient-years. Assuming a 70 year life a patient with persistent ductus arteriosus has a 20% risk of developing infective endocarditis. After surgical closure it is presumed that this risk declines to that...

Infective endarteritis in a 2-month-old infant associated with silent patent ductus arteriosus.

[Infective endarteritis in patent ductus arteriosus and septic pulmonary embolism].

Infective endarteritis was the most common cause of death in patients with patent ductus arteriosus (PDA) prior to the introduction of antibiotic therapy and surgical closure of the defect,1 though nowadays it is a rare complication.2 Infective endarteritis is especially unusual in asymptomatic patients, more so when the PDA is silent on cardiac auscultation, with very few reports of this type ...

Management of Infective Endocarditis

Infective endocarditis (IE) is an endovascular microbial infection of cardiovascular structures (e.g., native valves, ventricular or atrial endocardium) including endarteritis of the large intrathoracic vessels (e.g., in a patent ductus arteriosus, arteriovenous shunts, coarctation of the aorta) or of intracardiac foreign bodies (e.g., prosthetic valves, pacemaker or ICD leads, surgically creat...